Is May Apple Toxic to Dogs?
Also known as: American Mandrake, Wild Lemon, Ground Lemon, Podophyllum peltatum · Podophyllum peltatum
What makes it toxic
Podophyllotoxin, a lignan that halts cell division, concentrated in the rhizome and roots; leaves and unripe fruit carry smaller amounts. It chemically injures the lining of the digestive tract.
Warning signs to watch for
Profuse salivation, repeated vomiting, watery diarrhea and abdominal pain starting within a few hours, then dehydration, weakness and lethargy. Large doses can depress blood pressure and the nervous system.
What to do if your dog eats it
Contact your vet or an emergency clinic right away after any ingestion of root or plant material. Aggressive fluid support and anti-nausea care early prevent the dehydration that makes this poisoning dangerous.
Common questions
How much mayapple root is dangerous for a dog?
A chewed piece of root is enough to cause severe GI injury in a small dog. Treat any root ingestion as serious regardless of the dog’s size.
Why do woodlands full of mayapple not poison wildlife?
Native animals mostly avoid it or tolerate small amounts of ripe fruit. Dogs do not share those instincts or tolerances, so supervision is the defense.
More plants checked for dogs
This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate something concerning, contact your veterinarian or a pet poison hotline right away. Checking what your pet can eat? Visit our sister site SafeOrToxic.